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Researchers looking into whether GLP-1 drugs can help slow aging
Researchers are testing whether tirzepatide can slow biologic aging by 10% to 15%, building on early DNA-clock signals from prior studies.
Researchers at the University of Texas Medical Branch in Galveston, Texas, are leading a clinical trial to determine if tirzepatide, the active ingredient in Zepbound, can slow biologic aging.
Scientists are investigating whether GLP-1 medications may help slow the aging process, following past studies that are fueling interest in the class of drugs.
The UTMB trial will follow adults between the ages of 55 and 70 who qualify for weight loss treatment, monitoring biological age markers, inflammation, cognitive function, strength, and mobility.
After 32 weeks of semaglutide treatment, Dr. Michael Corley of UCSD reported that participants showed changes consistent with slower aging, calling the findings "a signal here that warranted future study."
Experts emphasize that no scientific evidence currently supports healthy people taking GLP-1s for longevity, though Dr. Thomas Blackwell of UTMB hopes the research will show a 10 to 15% slowdown in biologic aging.