Why People Said Oregon Psilocybin Services Improved Mental Well Being
The largest Oregon study of regulated psilocybin found most participants reported benefits and only a few serious adverse reactions.
- On Wednesday, an Oregon Health & Science University-led study published in JAMA Network Open found that 346 participants in Oregon's regulated psilocybin program reported improved mental health with high safety, marking the most rigorous analysis of the non-medical model to date.
- Oregon voters approved Measure 109 in 2020, establishing a non-medical model where adults 21 and older can access psilocybin at licensed service centers under supervision of trained facilitators without prescriptions or medical referrals.
- Among the 346 participants, most reported improved well-being, though four first-time users experienced "serious adverse reactions" requiring medical attention. Researchers noted these events were rare, occurring in 1.2% of the study group.
- Lead author Dr. Todd Korthuis told NPR "The data has swayed me," while Balzs Szigeti, a clinical data scientist at the University of California, San Francisco, said the program's safe operation is "definitely good news for psilocybin."
- OHSU researchers secured a $3.3 million, five-year federal grant to study psilocybin's effect on substance use, while the Oregon Health Authority discusses doubling licensing fees for centers and facilitators to address budget shortfalls.
12 Articles
12 Articles
Real-world study shows Oregon psilocybin services relieve mental health symptoms
People participating in an Oregon Health & Science University-led study of state-regulated psilocybin services reported relief from symptoms of anxiety, depression and post-traumatic stress disorder - with almost two-thirds declaring the experience to be among the most meaningful of their life.
Oregon's Psilocybin Program Helps People Improve Mental Health, Federally Funded Study Published By American Medical Association Shows
“They reported decreases in depression, anxiety, and posttraumatic stress disorder symptoms; improved life satisfaction; and improved mental wellbeing.” By Jack Gorsline, Psychedelic State(s) of America Oregon’s state-regulated psilocybin program has maintained a strong safety record while delivering measurable mental health improvements. But an impending financial crisis threatens to dismantle the nation’s first legal psilocybin market. A long…
A real-world study of Oregon's nonmedical psilocybin program shows promise
(JDawnInk)New research on the experiences of people who took magic mushrooms through Oregon's homegrown psychedelic industry — the first program of its kind in the U.S. — is offering a largely favorable picture. The study, based on almost 350 people who took the drug at state-licensed centers, is the most rigorous analysis yet of the real-world implications of regulated psilocybin, the active ingredient in magic mushrooms. Most of the participan…
Study finds lasting benefits among people using Oregon psilocybin services
People using Oregon’s state-regulated psilocybin services reported substantial improvements in symptoms of depression, anxiety and post-traumatic stress disorder during the first large multisite study of the program. The findings, published in JAMA Network Open, offer an early look at what happens when psychedelic services move beyond tightly controlled clinical trials and into a regulated, real-world setting. Nearly two-thirds of participants s…
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