Viking Therapeutics’ VK2735 Shows Strong Weight-Loss Retention With Monthly Dosing
The company said 180 adults with obesity maintained up to 97% of prior weight loss on every-other-week dosing and up to 90% on monthly dosing.
- On Tuesday, Viking Therapeutics announced positive top-line results from its VK2735-102 maintenance study, showing patients maintained significant weight loss after transitioning to less frequent dosing regimens.
- Following an initial 21-week induction period of weekly injections, the trial transitioned participants to monthly or every-other-week doses of VK2735 to evaluate long-term weight management and treatment adherence.
- Patients switching to every-other-week dosing maintained up to 97% of weight loss, while those on monthly dosing retained up to 90% over the following 12 weeks.
- "These results are important as they provide a basis for improved dosing flexibility," said Louis Aronne, MD, FACP, former president of The Obesity Society, noting excellent tolerability with GI-related adverse event rates similar to placebo.
- Analysts expect the obesity market to reach $100 billion in annual sales by 2030, as Viking prepares to study oral maintenance dosing in an upcoming trial to expand patient options.
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Viking Soars Alone as Obesity Complex Shrugs at Strong GLP-1 Results
Viking Therapeutics surged more than 26% on fresh GLP-1 maintenance data while every major obesity peer from Eli Lilly to Novo Nordisk barely registered a pulse, raising a pointed question about whether this catalyst belongs to Viking alone or signals something bigger.
Viking drug maintains up to 97% weight loss on less frequent dosing
Viking's VK2735 retained up to 97% of prior weight loss on every-other-week dosing and up to 90% monthly, versus 61% on placebo, in Sep 22, 2026 top-line data. · 19 sources across the spectrum on IJR News.
Viking Therapeutics’ VK2735 Shows Strong Weight-Loss Retention With Monthly Dosing
Viking Therapeutics (NASDAQ:VKTX) reported top-line results from a maintenance dosing study of VK2735, its dual GLP-1/GIP receptor agonist candidate for obesity, showing that participants retained much of their initial weight loss after transitioning from weekly treatment to every-other-week or mont
Viking Therapeutics' obesity drug shows durable weight-loss benefit ...
Viking Therapeutics VK2735 Obesity Drug Maintains Weight Loss Up to 97% as Shares Surge 40%
Viking Therapeutics said patients shifted to a less frequent dosing regimen of its experimental obesity treatment showed superior weight loss maintenance to those on placebo, in a study, sending its shares up 40% before the bell.The company said on Tuesday that patients who switched to an every-other-week dosing of VK2735 maintained up to 97% of the weight they had lost during an initial 21-week treatment period, while those on a monthly dosi…
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