US EditionCocktail of Three Supplements Improves Social Behaviors in Autistic Mice
A low-dose mix of zinc, serine, and branched-chain amino acids improved social behavior and neural communication in three autism mouse models, researchers reported.
- Researchers led by Tzyy-Nan Huang and Ming-Hui Lin report a low-dose mix of zinc, serine and branched-chain amino acids improved social behaviour in three mouse models of autism.
- Because nutrition influences neural connectivity, the team argued the three nutrients would better address ASD's abnormal neural connectivity and allow lower dosages.
- Using proteomics and imaging, proteomic analysis and in vivo calcium imaging of the basolateral amygdala showed restored synaptic proteins and reduced amygdala hyperactivity, while behavioural assays found changes after seven days.
- The researchers say the cocktail improved social behaviours across Tbr1+/−, Nf1+/− and Cttnbp2+/M120I mice, calling it a safer, practical approach that may eventually apply to children, with caution.
- Independent critics flagged missing interaction tests and experimental design elements such as control order and repeated testing, while Maria Knöbel, MBBS, and Eleni Nicolaou warned about supplement risks like insomnia and metabolic loads.
12 Articles
12 Articles
Simple nutrient mix delivers surprising autism breakthrough in mice
A low-dose mix of zinc, serine, and branched-chain amino acids boosted neural function and social behavior in autism mouse models. The combination restored more typical synaptic protein patterns and reduced excessive amygdala activity. Individual supplements had no effect, showing that the nutrients must work together. The findings point toward a promising multi-nutrient strategy for influencing brain circuits involved in autism.
Cocktail of three supplements improves social behaviors in autistic mice
Researchers led by Tzyy-Nan Huang and Ming-Hui Lin from Academia Sinica in Taiwan report that a low-dose mixture of zinc, serine, and branch-chain amino acids can alleviate behavioral deficits in three different mouse models of autism.
Simple Three-Nutrient Blend Rapidly Improves Autism Behaviors in Mice
A low-dose blend of zinc, serine, and branched-chain amino acids dramatically improved brain signaling and social behavior across three different mouse models of autism. Even brief treatment sparked real-time changes in neural connectivity, making this nutrient cocktail an intriguing path for future exploration. Low-Dose Nutrient Blend Shows Potential in Autism Mouse Models Researchers led by [...]
Supplement trio shows promise in reversing autism-linked behaviors in mice
Researchers led by Tzyy-Nan Huang and Ming-Hui Lin from Academia Sinica in Taiwan report that a low-dose mixture of zinc, serine, and branch-chain amino acids can alleviate behavioral deficits in three different mouse models of autism. Published in PLOS Biology, the study shows that when combined together, these three dietary supplements promote communication between neurons in the brain and improve social behaviors.
Three nutrients together may reduce autism, study finds
A new study from researchers in Taiwan has found that a mix of three nutrients—zinc, serine, and branched-chain amino acids—may help improve social behavior in mouse models of autism. The research, led by Tzyy-Nan Huang and Ming-Hui Lin at Academia Sinica, was published in the journal PLOS Biology on December 2nd. The scientists tested how […] The post Three nutrients together may reduce autism, study finds appeared first on Knowridge Science Re…
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