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Taxi Drivers Rarely Die of Alzheimer's. How Complex Mental Maps and Spatial Reasoning Protect Your Brain

Researchers found taxi and ambulance drivers had the lowest Alzheimer’s death rates among 443 occupations, with about 1 in 100 deaths attributed to the disease.

  • Researchers from Mass General Brigham analyzed death certificates for nearly 9 million adults between January 1, 2020 and December 31, 2022, finding that taxi and ambulance drivers had the lowest risk of dying from Alzheimer's disease out of 443 occupations examined.
  • Constant work of tracking destinations and updating mental maps exercises the hippocampus, a brain region governing memory that Alzheimer's often damages early, potentially providing protective benefits against the disease.
  • After adjusting for factors like age and education, roughly 1 in 100 taxi and ambulance drivers died of Alzheimer's, compared with 1 in 60 people overall; this advantage did not extend to other transportation jobs with predetermined routes.
  • Senior author Anupam Jena, MD, PhD, a physician in the Department of Medicine at Massachusetts General Hospital, noted the findings are "hypothesis-generating" rather than conclusive, though they suggest occupations may affect Alzheimer's risk.
  • This aligns with research on London taxi drivers who must memorize more than 25,000 streets to earn "The Knowledge," showing that sustained navigational demand can measurably change adult brain structure and protect against cognitive decline.
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Reproduction/TV Globo Taxi and ambulance drivers are less likely than workers from almost all other professions to die as a result of Alzheimer's disease. This was the surprising result of a 2024 study that analyzed the death certificates of nearly 9 million people in the United States. These results drew my attention because these two professions depend on the same thing as my own work: maps. I spent over two decades looking at maps.

·Rio de Janeiro, Brazil
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The Conversation broke the news in Boston, United States on Thursday, August 6, 2026.
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