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Pills or no pills? Study weighs antidepressant risk in pregnancy

Researchers found antidepressant exposure during pregnancy may raise some baby risks, while untreated depression also carries harms, the study said.

  • A University of Glasgow study published in PLOS Medicine suggests children of mothers with depression face higher risks of neurodevelopmental disorders. Researchers tracked more than 167,000 children born in Wales between 2009 and 2016.
  • Study leader Saraid McIlvride noted that while antidepressant use is increasing, untreated depression during pregnancy carries distinct risks. This makes informed medication decisions challenging when both the condition and drugs impact maternal and fetal health.
  • Data showed 24 in every 100 children of mothers with untreated depression had special educational needs, increasing by three in every 100 if mothers took antidepressants. This compared to 20 in every 100 for those unexposed to depression or drugs.
  • Researchers emphasize that women should not automatically stop taking antidepressants, as untreated depression can harm both mother and baby. Findings indicate that antidepressant exposure could serve as a marker for identifying children needing additional school support.
  • McIlvride added that linking mothers' and babies' routinely collected data is an amazing resource for maternal mental health research. Further studies are needed to empower women to make informed health decisions with their doctor or midwife.
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Pills or no pills? Study weighs antidepressant risk in pregnancy

A higher risk of children requiring special educational needs can't be attributed entirely to exposure in the womb to antidepressants.

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Daily Post-Athenian broke the news on Tuesday, September 29, 2026.
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