Chemotherapy-Free Treatment Shows Promise for some Patients with Metastatic Breast Cancer

Chemotherapy-free treatment shows promise for some patients with metastatic breast cancer

Researchers at the Icahn School of Medicine at Mount Sinai found that a chemotherapy-free combination of four targeted therapies showed encouraging results in patients with HR-positive, HER2-positive metastatic breast cancer, offering a potential first-line treatment option that may be more convenient for some patients and avoids chemotherapy.

Mount Sinai Finds Chemo-Free Treatment Promising for Some Metastatic Breast

New York, New York, August 20, 2026 — A chemotherapy-free combination of four targeted treatments has produced encouraging and durable results in people with hormone receptor-positive, HER2-positive metastatic breast cancer, according to researchers at the Icahn School of Medicine at Mount Sinai. Findings from the multicenter phase 1/2 ASPIRE clinical trial suggest that combining hormone-blocking […]

Mount Sinai Study Finds Chemotherapy-Free Treatment Shows Promise for Some Patients With Metastatic Breast Cancer

Researchers at the Icahn School of Medicine at Mount Sinai found that a chemotherapy-free combination of four targeted therapies showed encouraging results in patients with HR-positive, HER2-positive metastatic breast cancer, offering a potential first-line treatment option that may be more convenient for some patients and avoids chemotherapy.