More Than a Third of 1.1 Million Adults Prescribed GLP-1s Without Documented Diabetes or Obesity Had Normal Weight

Over 1 Million Americans Take GLP-1 Drugs Like Ozempic With No Documented Medical Need

A major study reveals over 1.1 million Americans received GLP-1 prescriptions like Ozempic without documented diabetes or qualifying obesity, with rates rising 15-fold from 2021 to 2025. Many had normal BMI and higher rates of eating disorders. The trend raises serious questions about risks, access and long-term effects in lower-need populations.

More Than 1 Million Americans Are Taking Ozempic and Other GLP-1s Without an Approved Reason. Is That Actually a Problem?

New research shows that off-label use of GLP-1s has surged in recent years.

Over 1.1M people using GLP-1 drugs without FDA-approved reason

Researchers say little is known about the risks of GLP-1s for people who don't have an approved medical condition.

More Than a Third of 1.1 Million Adults Prescribed GLP-1s Without Documented Diabetes or Obesity Had Normal Weight

A study of more than 92 million health records found that 1.1 million adults got GLP-1 drugs without documented diabetes or obesity. What the data show and don't show.