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Jamie Lynn Sigler Talks Multiple Sclerosis, a New Memoir and Finding Acceptance in Midlife

Summary by HealthyWomen
You probably recognize actress Jamie Lynn Sigler from her role as Meadow on the award-winning drama, The Sopranos. On screen, life for the Sopranos family was complicated and often shrouded in secrecy. Off camera, Sigler was dealing with a secret of her own: She was living with relapsing multiple sclerosis (RMS) — a chronic disease that can affect the brain, spinal cord and optic nerves and causes unpredictable flare-ups.Siegler was just 20 year…
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HealthyWomen broke the news on Tuesday, June 16, 2026.
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