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College football picks: Predictions against the spread, odds, betting lines for top 25 games in Week 4

Week 4 features six ranked matchups, with USA TODAY Sports experts weighing in on spreads, scores and odds for top-25 college football games.

Summary by thepress.net
A closer look at the top games in a loaded Week 4
Podcasts & Opinions

5 Articles

thepress.netthepress.net
Center

College football picks: Predictions against the spread, odds, betting lines for top 25 games in Week 4

A closer look at the top games in a loaded Week 4

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New York PostNew York Post
Lean Right

College football Week 4 predictions: Best bets, picks against the spread

Howie Kussoy, also known as the Pigskin Profit, is taking the favorite in Oregon-USC on Saturday.

·New York, United States
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USA TodayUSA Today
Lean Left

College football Week 4 picks: Expert predictions, odds for every top 25 game

Texas at Tennessee, Ole Miss at Florida and Oregon at USC headline Week 4 top-25 college football games. Here's how our experts are picking the games:

·New York, United States
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saturdaydownsouth.comsaturdaydownsouth.com

Friday Forecast: SDS Staff picks 5 Week 4 matchups against the spread

This week's Friday Forecast features our staff picks for electric games such as Texas at Tennessee and Ole Miss at Florida.

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Fox SportsFox Sports

College Football Week 4 Odds, 5 Sleeper Games To Watch

Check out the odds for five sleeper games as college football season enters Week 4.

·Los Angeles, United States
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Bias Distribution

  • 34% of the sources lean Left, 33% of the sources are Center, 33% of the sources lean Right
34% Left

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Fox Sports broke the news in Los Angeles, United States on Wednesday, September 23, 2026.
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