Picture an earnings call where one question keeps looping: can two fast-growing immunology drugs really replace a mega-blockbuster that defined a decade of pharma profits? That’s the AbbVie story in a sentence. Portfolio managers now model every quarter around the same pivot: Humira is sliding post-biosimilars; Skyrizi and Rinvoq are sprinting. The gap is the whole ballgame. If you care about cash flow durability, margins, and what happens when …
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