How a Century-Old Solvent Can Enable Efficient Amide Synthesis

How a century-old solvent can enable efficient amide synthesis

Amide bonds are chemical linkages essential to biology, medicine and materials chemistry. Peptide bonds, a class of amide bonds, link amino acids to form proteins. Amide bonds are also important in medicines and polymers. Efficient synthesis of amide bonds remains a major focus in green chemistry.

Century-Old Solvent Dichloromethane Emerges as Surprising Coupling Reagent

One of the most familiar liquids in the organic chemistry laboratory has just revealed a hidden talent. Dichloromethane, a solvent that has been in routine use for more than a century and sits in virtually every fume hood in the world, can do far more than dissolve reactants. A research team led by Professor Sunwoo […]

Chonnam University Researchers Discover How a Century-Old Solvent Can Solve Efficient Amide Synthesis

Researchers develop an efficient and scalable approach to amide synthesis using the commonly used solvent dichloromethane JEOLLANAM-DO, South Korea, Sept. 25, 2026 /PRNewswire/ — Amide bonds are chemical linkages that are essential in biology, medicine and materials chemistry. Peptide bonds, a class of amide bonds, link amino acids together to form proteins. They are also important for medicines and making polymers. Efficient synthesis of amide …