Japanese Hospital Performs First Surgery Using Heart Muscle Stem Cells
The hour-long procedure used commercially available stem-cell sheets and is expected to improve heart function in patients with ischemic heart disease.
- On Tuesday, surgeons at Osaka Keisatsu Hospital in Osaka City performed the world's first transplant of "RiHeart" cardiac muscle cell sheets into a patient in her 50s, marking a clinical milestone for regenerative therapy.
- Hospital President Sawa Yoshiki developed the technology with Nobel Prize winner Shinya Yamanaka, and the government granted conditional approval in March for the therapy using IPS cells.
- Trials involving eight patients with ischemic heart disease showed symptom relief, including improved cardiac performance, while IPS cells are created by stimulating specialized cells back into a juvenile state.
- Following the hour-long procedure, the patient remains in stable condition, and "RiHeart" sheets became eligible for health insurance coverage as of September.
- Sawa aims to expand the treatment to 75 patients across about 20 medical facilities by 2033, though the Asahi Shimbun reported that full authorization depends on proving safety and efficacy over the next seven years.
24 Articles
24 Articles
Japanese hospital performs first surgery using heart muscle stem cells
A hospital in Japan has carried out the world's first surgery using sheets of commercially available heart muscle stem cells after the groundbreaking therapy was approved this year, one of the surgeons said.
During this one-hour intervention, on Tuesday, a woman of about 50 years of age who suffered from severe heart failure was placed in the heart of three layers of cardiomyocytes derived from iPS cells (induced pluripotent stem cells).This procedure marks the first clinical use of this regenerative therapy since its conditional approval by the Japanese government in March. In the trials, the eight patients treated, who suffered ischemic heart dise…
The intervention was carried out in Japan on a patient with severe heart failure and marks the first clinical use of an iPS-based technology, the discovery that earned Shinya Yamanaka the Nobel Prize in 2012
A hospital in Japan performed the first surgery in the world using commercially available heart muscle stem cell blades. The procedure was performed on Tuesday (29) in a 50-year-old woman suffering from severe heart failure, according to Yoshiki Sawa, a surgeon responsible for the operation.
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