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AbCellera Stock Soars 35% on Successful Clinical Trial Result

The treatment cut hot flash frequency and severity after one dose, with 92 postmenopausal women enrolled and no serious adverse events reported.

  • On Monday, AbCellera Biologics Inc. reported positive Phase 2 results for ABCL635, its experimental menopause treatment, sending shares soaring 35% by market close on August 10, 2026.
  • The multicenter study enrolled 92 postmenopausal women to evaluate the non-hormonal, subcutaneous injection targeting the neurokinin 3 receptor , which regulates body temperature and alleviates moderate-to-severe hot flashes.
  • ABCL635 participants experienced an 83% reduction in hot flash frequency versus 33% for placebo, while 58% reported less severe symptoms compared to 12% in the placebo group after four weeks.
  • BMO Capital Markets analyst Evan Seigerman called the results "transformational," estimating a $6 billion global market opportunity and forecasting potential peak annual sales of about $2.3 billion for ABCL635.
  • AbCellera plans to publish additional 12-week trial data later this year, though regulatory approval requires success in an expanded efficacy trial, a considerable challenge for late-stage drug candidates.
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Rutland Herald broke the news on Monday, August 10, 2026.
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