Medically reviewed by Isabel Casimiro, MD, PhDStrength training is one key component to maintaining muscle when using GLPs.Credit: Ridofranz / Getty ImagesKey TakeawaysGlucagon-like peptide-1 (GLP-1) are typically prescribed for diabetes management or weight loss in those who need them.Using GLP-1s alongside a weight-loss diet may cause rapid weight loss, which may result in the loss of some muscle mass and bone density.Meeting protein recommend…