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What to know about Cushing’s syndrome, which led to Amy Schumer's dramatic weight loss

Summary by Fox News
Comedian Amy Schumer, 44, has recently come clean about her struggle with Cushing’s syndrome, leading to a dramatic weight loss.Schumer's transformation has sparked conversation online, to which she responded in a now-deleted Instagram post that shut down speculation about cosmetic enhancements."I didn’t lose 30lbs — I lost 50," she emphasized on social media, adding that she does not get Botox or filler.AMY SCHUMER DROPPED 50 POUNDS TO BATTLE D…

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Fox News broke the news in New York, United States on Saturday, December 13, 2025.
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