Chronic Bowel Disease Involves Multiple Types of Inflammation Happening at Once, Study Reveals

Chronic bowel disease involves multiple types of inflammation happening at once, study reveals

Chronic immune diseases are shaped by multiple inflammatory processes happening at the same time, each in different parts of the tissue. This finding from Karolinska Institutet, published in the journal Immunity, is based on a mouse study. The research may help explain why patients respond differently to treatment.

Scientists Flip Immune System “Switch,” Uncover Surprising Path To Stop Gut Inflammation

Scientists have uncovered an unexpected mechanism by which the gut’s immune system maintains balance, challenging long-standing assumptions about how immune tolerance is regulated. Researchers at Weill Cornell Medicine have uncovered an unexpected mechanism the immune system uses to prevent chronic inflammation in the intestine. The discovery could point to new treatment strategies for inflammatory bowel [...]

Lactobacillus brevis Cell-Free Supernatant Recalibrates TLR-Mediated Inflammatory Signaling While Preserving Immune Competence in HT-29 Intestinal Epithelial Cells

Background Dysregulated Toll-like receptor (TLR) signaling in intestinal epithelial cells contributes to persistent mucosal inflammation in inflammatory bowel disease (IBD). Although Lactobacillus brevis has demonstrated anti-inflammatory potential, the pathway-level mec...

Scientists Flip Immune System “Switch,” Uncover Surprising Path To Stop Gut Inflammation - Archyworldys

Researchers at Weill Cornell Medicine identified a mechanism to prevent chronic intestinal inflammation in a study published April 24 in the Journal of

What immune switch stops gut inflammation?

A new mechanism for immune tolerance in the gut Researchers report that the gut’s immune system uses an unexpected “switch” mechanism to maintain balance and prevent runaway inflammation. The work challenges longstanding assumptions about how immune tolerance is generated in the intestinal…