What Channel Is Rams vs 49ers Game on TV Tonight? TNF Start Time, NFL Schedule, Streaming
The 49ers overcame multiple injuries and won 26-23 in overtime with Eddy Piñeiro’s decisive field goal, improving to 4-1 and taking sole NFC West lead, officials said.
- On Oct. 2, 2025, the San Francisco 49ers and Los Angeles Rams will kickoff at 8:15 p.m. ET at SoFi Stadium, streaming nationally on Amazon Prime Video and NFL+ with local simulcasts.
- With NFC West parity high, this matchup hands the winner a short-term division lead as both the San Francisco 49ers and Los Angeles Rams enter NFL Week 5 tied at 3-1.
- Listed inactives show the 49ers' injury issues going into the game with Brock Purdy, George Kittle, Jauan Jennings and Ricky Pearsall all sidelined, while Al Michaels, Kirk Herbstreit and Kaylee Hartung call the game.
- ESPN's model projects the Rams as slight favorites with a 57.2% win probability, and a victory moves the winner to 4-1 with an early NFC West edge.
- In a recent chapter of the rivalry, the 49ers prevailed 26-23 in overtime with Eddy Piñeiro's field goal before 73,652 fans at SoFi Stadium.
42 Articles
42 Articles

49ers hold off Rams in NFL overtime thriller
San Francisco's Eddy Pineiro booted a 41-yard field goal in overtime and the 49ers defense came up big in a tense 26-23 NFL victory over the Los Angeles Rams on Thursday.


4th-down stop in OT seals 49ers' victory over Rams
Eddy Pineiro kicked a 41-yard field goal and the San Francisco defense stuffed the Rams on fourth down later in overtime as the 49ers notched a 26-23 win over Los Angeles on Thursday night at Inglewood, Calif.

Short-handed 49ers stop Rams on downs in overtime, preserving a 26-23 victory
Eddy Piñeiro hit a 41-yard field goal in overtime before the San Francisco defense stopped Kyren Williams on fourth down with 3:36 to play, and the short-handed 49ers hung on for a thrilling 26-23 victory over the Los Angeles Rams, Mac Jones passed for 342 yards and two touchdowns for the 49ers, who
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