Vitamin D may prevent diabetes in people with certain genes
The benefit was seen only in people with AC or CC vitamin D receptor variants, while about 30% with AA variants saw no reduction in risk.
- Tufts University researchers discovered that daily Vitamin D supplements can lower diabetes risk in prediabetic adults, though effectiveness depends on specific genetic variations in the vitamin D receptor gene.
- The large D2d study originally tested 4,000 units of Vitamin D daily versus placebo in more than 2,000 prediabetic adults but found no significant risk reduction across all participants, prompting genetic analysis.
- Genetic analysis revealed that 30 per cent of the population carries the AA variation and did not respond to treatment, while those with AC or CC variations saw a 19% lower diabetes risk.
- This discovery suggests a personalized approach for the 115 million Americans with prediabetes, potentially involving an inexpensive genetic test to identify patients most likely to benefit from supplementation.
- Researchers cautioned against taking high doses without medical advice, as current guidelines recommend 600 IU for those under 70 and 800 IU daily for those older, since excessive intake can be harmful.
12 Articles
12 Articles
Study Sheds Light on Why Taking Vit D May Lower Diabetes Risk for Some
(MedPage Today) -- Vitamin D supplementation may help stave off the progression from prediabetes to type 2 diabetes, but only for individuals with certain genetic profiles, data from the D2d trial indicated. Among 2,098 adults with prediabetes...
High-Dose Vitamin D Supplements May Reduce Diabetes Risk By 19% In Genetically Predisposed Adults: Study
The study involved adults who took either 4,000 IU of vitamin D daily or a placebo for about 2.5 years. While the original D2d results didn't show any drop in overall diabetes risk across all participants, the new study revealed targeted benefits.
An American study examined the effects of vitamin D in adults with prediabetes. It doesn't help everyone, but it can delay the development of serious complications for many.
Vitamin D may help prevent diabetes, depending on genes
More than two in five U.S. adults have prediabetes, a condition marked by higher-than-normal blood sugar levels that often leads to type 2 diabetes. A new study finds that vitamin D may help delay or prevent that progression, but only in people with certain genetic variations.
Coverage Details
Bias Distribution
- 43% of the sources lean Left, 43% of the sources are Center
Factuality
To view factuality data please Upgrade to Premium
