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Two Deaths Linked to Rabies-Infected Kidney Transplant

The CDC confirmed infection from a donor kidney after a skunk scratch went unrecognized, prompting post-exposure prophylaxis for 46 contacts including healthcare workers and cornea recipients.

  • On Dec. 8, 2025, the U.S. Centers for Disease Control and Prevention confirmed a Michigan kidney transplant recipient died weeks after surgery, linked to the donor kidney in a rare rabies case causing two deaths.
  • Because rabies testing on donor organs is not routine, the Idaho man's skunk scratch in late October went unrecognized until early December, delaying transplant teams.
  • About five weeks after the transplant, the Michigan kidney recipient developed tremors, weakness, confusion, urinary incontinence, fever, and hydrophobia, while CDC laboratory testing detected rabies virus RNA in recipient samples and the donor's remaining kidney with a bat-linked rabies strain.
  • Public health officials assessed 357 possible contacts and 46 people, including cornea recipients, were advised to receive PEP; doctors removed transplanted corneas after one tested positive.
  • The CDC advises transplant teams to exercise greater caution when donors have animal exposures, noting rabies testing is not routine due to fewer than 10 human rabies deaths annually and over 3,500 animals testing positive yearly amid 2024 U.S. transplant volume of 48,149 from 24,018 donors.
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Two Deaths Linked to Rabies-Infected Kidney Transplant

Key Takeaways

A Michigan resident died in January 2025 after contracting rabies following a kidney transplant in December 2024 at an Ohio hospital. Man dies of rabies from infected kidney. A public health investigation, confirmed by the Centers for Disease Control and Prevention (CDC) rabies laboratory, determined that the infection originated in the transplanted organ. According to authorities, the donor had been exposed to a wild animal in Idaho weeks earli…

American epidemiologists have shed light on why a Michigan man died five weeks after receiving a new kidney.

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Science Alert broke the news in Australia on Monday, December 8, 2025.
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