US EditionSpanish team cures pancreatic cancer in mice
- This month, the CNIO study published in PNAS found a triple-drug treatment entirely eliminated pancreatic tumors in mice, led by Mariano Barbacid.
- Because pancreatic cancer is unusually lethal, more than 50,000 Americans die annually and only about 12 percent survive five years, the University of Utah Huntsman Cancer Institute reports.
- Using a three-drug strategy, CNIO researchers say the triple therapy targets multiple tumor survival mechanisms, but study authors warn optimising it for patients will be complex and clinical trials are premature.
- Study authors said the findings open new therapy designs and guide clinical trials, but Simon Maechling, Ph.D. chemist, cautions human insights may take eight to 10 years.
- Observers warn that headline promises of a cure from mouse results mislead the public, though research commentators describe this as real progress against pancreatic cancer this month.
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105 Articles
Pancreatic tumors eliminated in mice without resistance developing
Current drugs for pancreatic cancer lose effectiveness within months because the tumor becomes resistant. Now, a group from Spain's National Cancer Research Centre (CNIO) has been able to avoid the development of resistance in animal models with a combined triple therapy. Mariano Barbacid, head of the Experimental Oncology Group at the CNIO, has designed a therapy that successfully eliminates pancreatic tumors in mice completely and durably, wit…
A team of Spanish researchers published an encouraging study in the treatment of pancreatic cancer. They eradicated tumours in mice. In "Hello! Morning TF1", Vincent Valinducq takes stock. - Pancreatic cancer: Spanish researchers manage to completely eliminate cancer cells in mice (Health and well-being).
The CNIO researcher explains that the triple attack eliminates relapse-free tumors after years of trials and opens the way to a drug without chemotherapy.
This Monday, El Hormiguero received a double visit. Pablo Motos first interviewed singer Mika and then Dr. Mariano Barbacid and Lola Manterola of CRIS against cancer.The presenter welcomed them and explained the reason for their presence in the program, the doctor and his team had managed to completely eliminate pancreatic cancer in animals.It is something unpublished so far in one of the most aggressive and silent tumors. "We were already carry…
In the last days of January, the news of science was that at the National Center for Oncological Research (CNIO) in Spain, a team led by Mariano Barbacid eliminated in mice the most common pancreatic cancer, ductal adenocarcinoma, with a combination therapy of three drugs that prevents the appearance of resistances and that has no important side effects.
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