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Transplanted hearts adjust their biological age to that of their host

Researchers found donor hearts adopt the biological age of recipients, with 11 human transplants and mouse grafts showing the same pattern.

Summary by Nature
Nature, Published online: 28 September 2026; doi:10.1038/d41586-026-03043-wTracking the biological age of grafted organs suggests that donor pools could be expanded to boost organ availability.

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Ali Hajiluyi/Unsplash. Transplanted hearts can change their biological age after surgery and start to behave according to the recipient's body. This is what indicates a new study that analyzed this process in animals and human patients.The results suggest that older organs can work better than you imagined in younger people.The research, published on the bioRxiv pre-print server, has not yet been peer reviewed.How the heart changes after transpl…

·Brasília, Brazil
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What happens to organs after transplantation? Hearts from young donors age rapidly in the bodies of older recipients, while older hearts are rejuvenated inside young ones.

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Nature broke the news in London, United Kingdom on Monday, September 28, 2026.
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