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Train derails in Affton, HAZMAT crews respond

More than a dozen families evacuated after three train cars overturned near Weber Road in Affton, with hazmat crews confirming cars were empty, officials said.

AFFTON, Mo. - Multiple railcars for a train derailed Friday afternoon in Affton near Weber Road and New Hampshire Avenue on Friday. Investigators say the train derailed around 4:30 p.m. HAZMAT crews have been called to check out tanks on the train. Drivers are asked to avoid the area as crews work to investigate the derailment and clear the scene. The area is currently blocked, FOX 2 has learned. Sources tell FOX 2 that evacuations are underway …

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KSDK broke the news in St. Louis, United States on Friday, October 10, 2025.
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