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TPGS-coated zein nanoparticles encapsulating Haematococcus pluvialis extract for Alzheimer’s disease: An in vitro evaluation towards brain-targeted delivery
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TPGS-coated zein nanoparticles encapsulating Haematococcus pluvialis extract for Alzheimer’s disease: An in vitro evaluation towards brain-targeted delivery
Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by β-amyloid (Aβ) aggregation and limited treatment efficacy due to the restrictive nature of the blood-brain barrier (BBB). To address this, we developed d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS)-coated Zein nanoparticles (Hp-Zein-TPGS NPs) encapsulating Haematococcus pluvialis (Hp) extract as a brain-targeted drug delivery system. Hp-Zein…
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