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The push to end animal testing is gaining steam, but technology can’t fill the gap yet

FDA and NIH promote nonanimal testing alternatives with $150 million NIH investment, while experts acknowledge existing technologies can't yet replace all animal research roles.

  • On Wednesday, the FDA issued draft guidance on nonanimal testing, with HHS Secretary Robert F. Kennedy Jr. saying it advances a commitment to human-relevant methods.
  • Building on moves last year, the federal government shifted policies with the FDA Modernization Act 2.0 removing animal-study mandates and the NIH launching initiatives to reduce animal use.
  • Experts note that more than 3.18 million animals were used in USDA-licensed facilities and at least 111 million more if common lab species are included; some programs average 144 monkeys, but alternatives cannot yet answer all full-body questions.
  • The NIH said this week that it is investing $150 million and creating seven technology development centers, even as it provided $2.2 billion in contracts or grants to foreign organizations for animal research from FY2011 through FY2021.
  • Polling shows that public tolerance for animal testing fell from 65% in 2001 to 47% in a September Gallup poll, while all three 2025 Nobel Prize winners in medicine used mice and Dr. Emma Robinson says animal research remains crucial.
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The push to end animal testing is gaining steam, but technology can’t fill the gap yet

The FDA has released draft guidance that aims to clear up how drug developers can use alternative testing – but that doesn’t mean animal testing in the US is over.

·Atlanta, United States
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CNN broke the news in Atlanta, United States on Friday, March 20, 2026.
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