The drug used in Tennessee’s failed execution has come under past scrutiny
Governor Bill Lee ordered a third-party review after the first known pentobarbital execution failure and said no other Tennessee execution will occur this year.
- On Wednesday, Tennessee's attempt to execute Christa Pike failed after two doses of pentobarbital were administered; officials have not explained the malfunction, and it remained unclear on Thursday whether Pike was still alive.
- President Donald Trump resumed federal executions during his first term, adopting pentobarbital to replace older three-drug protocols, and the Justice Department reauthorized the drug's use in 2026 after his return to power.
- Tennessee's guidelines require a 5 gram dose of pentobarbital; experts cited in a 2025 federal review warned the drug may cause pulmonary edema, creating a sensation of suffocating before unconsciousness occurs.
- Republican Gov. Bill Lee ordered a third-party review of the failed execution and announced that no further executions will take place in Tennessee this year.
- Other states including South Carolina, Georgia, and Texas utilize pentobarbital with varying protocols; however, a 2025 federal review concluded, "there remains significant uncertainty about whether the use of pentobarbital as a single drug lethal injection causes unnecessary pain and suffering.
24 Articles
24 Articles
What to know about pentobarbital after death row inmate survives 2 lethal injection doses
Pentobarbital is the barbiturate used in Christa Pike's failed Tennessee execution. Here's how the lethal injection drug works and why it can fail to cause death.
Botched Execution Puts Sedative in the Spotlight
The drug used by Tennessee in its unsuccessful attempt to execute Christa Pike on Wednesday night is more generally used to treat emergency seizures than end lives. Pentobarbital, commonly sold as Nembutal, is a short-acting barbiturate that depresses the central nerve system, explains USA Today. It's primarily used as a...
Drug used in failed Christa Pike execution faced past scrutiny
Tennessee governor calls Christa Pike's failed execution 'deeply disturbing' and orders a review
Tennessee officials haven't yet explained what went wrong during the failed execution of Christa Pike, which was called off after she was given an initial and a backup dose of the drug meant to kill her. Pike's condition was unclear…
Tennessee governor calls Christa Pike’s failed execution ‘deeply disturbing’ and calls for a review
Tennessee officials haven’t explained yet what went wrong during the failed execution of Christa Pike, which was called off after she was given an initial and a backup dose of the drug meant to kill her.
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