Study reveals a previously unknown ability of the brain to repair itself
Researchers found a specialized astrocyte group can rebuild damaged brain tissue in living mice by moving newly formed nuclei across lesion edges.
- Researchers at the University of Zurich identified a previously unknown mechanism where adult mouse brains repair tissue after focal injury, as published in Nature Neuroscience.
- Scientists previously assumed the adult brain could not fully replace astrocytes, which nourish neurons and regulate blood flow, after injuries or autoimmune disorders like neuromyelitis optica spectrum disorder.
- Using in vivo two-photon microscopy, researchers led by Bruno Weber, Marina Herwerth, and Matthias Wyss observed that 'regenerative' astrocytes remain at the lesion perimeter, sending newly formed daughter cell nuclei gliding through cellular extensions.
- Weber stressed that identifying genes and signaling pathways activated during repair provides potential targets for future therapeutics, which could help promote restoration of damaged brain tissue.
- While this study focused on mouse models, the findings suggest a self-healing capacity that may extend to humans, offering new avenues for treating neurological disorders and brain injuries.
11 Articles
11 Articles
Researchers at the University of Zurich show how the brain replaces cells and repairs tissues after accidents or diseases, which could open up new therapeutic approaches.
This mechanism is impossible to explain accurately because there are data that are unknown as they have to do with the unconscious part of the mind and with memories, beliefs and expectations Read
Scientists discover gene that helps the brain repair itself
A surprising discovery from high-altitude animals like yaks and Tibetan antelopes could reshape how we treat nerve damage in humans. Scientists found that a genetic mutation helping these animals survive low-oxygen environments also protects and repairs the myelin sheath—the vital coating around nerve fibers that’s damaged in diseases like multiple sclerosis (MS) and cerebral paralysis.
The brain may regenerate from injury better than previously thought. Scientists have discovered astrocytes that rebuild damaged areas of the mouse brain. The article, "How Do Brain Cells Regenerate? Better Than Previously Thought," comes from the website Everything That Matters.
Coverage Details
Bias Distribution
- 60% of the sources are Center
Factuality
To view factuality data please Upgrade to Premium
