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Study Results: Centralized Normothermic Preservation and Assessment Center Used to Rescue Kidneys
The study found 94 of 104 declined kidneys were transplanted after centralized assessment, with 6-month graft function comparable to standard cases.
On Monday, 34 Lives, PBC released study results in the American Journal of Transplantation demonstrating a 90% rescue rate for previously declined donor kidneys using centralized perfusion technology.
More than 9,000 recovered kidneys went unused in 2024, representing a 30% nonuse rate as geographic barriers and logistical constraints push cold ischemic times beyond the standard 24-hour limit.
Using Normothermic Machine Perfusion , researchers assessed 104 kidneys, measuring viability through the Hosgood score to evaluate renal flow, urine output, and macroscopic perfusion quality.
Despite median cold ischemia times of 37.6 hours versus 22.1 hours, the NMP cohort demonstrated a 26.3% delayed graft function rate compared to 60.2% in control groups.
According to Chris Jaynes, 34 Lives CEO and study Principal Investigator, these findings suggest NMP may have a promising role in ensuring no donated kidney is left behind.