Study finds Ozempic, Wegovy ingredient shows promise for alcohol use disorder in people with obesity
The 6-month trial found lower cravings and less overall drinking, though researchers said the mechanism is still unclear.
- Semaglutide cut heavy drinking days by about 41% in a study of 108 obese adults with alcohol use disorder, researchers at the Mental Health Center Copenhagen reported Thursday.
- The Lancet-published study marks the first randomized controlled trial testing GLP-1 drugs for alcohol use disorder, tracking participants over 26 weeks as they received weekly shots alongside psychotherapy.
- Endocrinologist Dr. Pessah-Polluck stated semaglutide "may be more effective than any of the current FDA-approved medications," while researchers speculated the treatment engages metabolic and reward pathways.
- Study author Dr. Anders Fink-Jensen noted the "strong reduction in the placebo group" likely stemmed from psychotherapy, while the trial included mostly white participants requiring diverse follow-up research.
- Experts warned patients using non-regulated GLP1s "don't exactly know what you are getting," citing risks of "dosing, impurities, additives" that could impede broader clinical adoption.
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Novo obesity shot Wegovy helped alcoholics drink less in study
By Naomi Kresge, Bloomberg News Novo Nordisk A/S’s obesity shot Wegovy helped people with alcoholism reduce their drinking, in the first controlled study of patients who sought help with their addiction. Volunteers on Wegovy reported drinking heavily for five days in a 30-day period after six months of treatment, 12 fewer days than before they started. The improvement showed in other measures of addiction, such as total alcohol consumption and b…
Semaglutide reduces heavy drinking for adults with alcohol use disorder, obesity
Once-weekly semaglutide was tied to a reduction in heavy drinking days among adults with obesity and alcohol use disorder, according to findings from a randomized controlled trial published in The Lancet.
Users of the weight-loss drug Ozempic crave less alcohol. This is shown in a study in the scientific journal The...
A recent study shows that people who received semaglutide drank less. How relevant are these results?
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