Report Shows Ketamine Deaths Soared Drastically in Last Decade
Deaths involving illicit ketamine in England, Wales, and Northern Ireland increased twenty-fold since 2014, with 85% of fatalities between 2020 and 2024 involving men, driven by polydrug use.
- Researchers from King's College London found that illicit ketamine-related deaths increased twenty-fold since 2014 across England, Wales and Northern Ireland, according to the September 29 study in the Journal of Psychopharmacology.
- Experts found increasing polydrug involvement as opioids, cocaine, benzodiazepines and gabapentinoids were frequently co-implicated, and mixing ketamine with depressant drugs raised overdose risk.
- Analysis of coroners' reports found 696 fatalities with illicit ketamine detections between 1999 and 2024, rising from six in 1999 to 123 projected deaths in 2023, with 85% men between 2020 and 2024.
- Researchers are calling for expanded drug checking, overdose prevention, treatment integration, and Clare Rogers urged reclassifying ketamine to Class A alongside better education.
- Researchers warn single-substance policies are unlikely to address harms as deaths shift to older, socioeconomically disadvantaged and dependent users, urging a broader public-health response.
27 Articles
27 Articles

Study finds ketamine deaths soared drastically in last decade
Experts say their findings raise doubts over whether single-substance drug policies can work.
Ketamine deaths have increased 20-fold since 2015 with mixing drugs on the rise, UK analysis finds
Deaths due to illicit ketamine use have increased 20-fold since 2015—but these deaths are increasingly occurring in complex polydrug settings, raising doubts over whether single-substance drug policies can reduce harms.
Study shows big cause of ketamine deaths
Deaths linked to illicit ketamine use in the UK have risen sharply over the past decade, with a 20-fold increase since 2015. But new research suggests that these deaths are rarely due to ketamine alone. Instead, they are increasingly tied to complex and dangerous patterns of polydrug use, raising doubts about whether reclassifying the drug […] The post Study shows big cause of ketamine deaths appeared first on Knowridge Science Report.
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