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Report Shows Ketamine Deaths Soared Drastically in Last Decade

Deaths involving illicit ketamine in England, Wales, and Northern Ireland increased twenty-fold since 2014, with 85% of fatalities between 2020 and 2024 involving men, driven by polydrug use.

  • Researchers from King's College London found that illicit ketamine-related deaths increased twenty-fold since 2014 across England, Wales and Northern Ireland, according to the September 29 study in the Journal of Psychopharmacology.
  • Experts found increasing polydrug involvement as opioids, cocaine, benzodiazepines and gabapentinoids were frequently co-implicated, and mixing ketamine with depressant drugs raised overdose risk.
  • Analysis of coroners' reports found 696 fatalities with illicit ketamine detections between 1999 and 2024, rising from six in 1999 to 123 projected deaths in 2023, with 85% men between 2020 and 2024.
  • Researchers are calling for expanded drug checking, overdose prevention, treatment integration, and Clare Rogers urged reclassifying ketamine to Class A alongside better education.
  • Researchers warn single-substance policies are unlikely to address harms as deaths shift to older, socioeconomically disadvantaged and dependent users, urging a broader public-health response.
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27 Articles

The Norfolk Daily NewsThe Norfolk Daily News
+11 Reposted by 11 other sources
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Report shows ketamine deaths soared drastically in last decade

Experts say their findings raise doubts over whether single-substance drug policies can work.

Daily JournalDaily Journal
+9 Reposted by 9 other sources
Center

Study finds ketamine deaths soared drastically in last decade

Experts say their findings raise doubts over whether single-substance drug policies can work.

·Cherokee County, United States
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Medical Xpress broke the news in on Monday, September 29, 2025.
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