Landmark Map of Human Brain’s Gene Activity Holds Clues to Alzheimer’s Disease and More
The map links inherited risk to more than 14,000 genes and shows shared and disease-specific patterns across Alzheimer’s, Parkinson’s and schizophrenia.
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6 Articles
Laboratory assistant holds a hemisphere of a healthy human brain at Belle Idee University Hospital in Chene-Bourg, near Geneva. March 14, 2011. REUTERS/Denis Balibouse Scientists created a detailed map of gene activity in a crucial part of the brain called prefrontal cortex, obtaining new insights into normal development and major brain diseases such as Alzheimer's, Parkinson's and schizophrenia. In nine separate studies, researchers examined ch…
Scientists map gene activity in brain’s prefrontal cortex
By Will Dunham WASHINGTON, Sept 23 (Reuters) - Scientists have created a detailed map of gene activity within a crucial part of the brain called the prefrontal cortex, gaining insight into normal development and major brain disorders such as Alzheimer'...
An extensive map of brain gene activity shows biological changes that may be involved in health and the possibility of disease
Landmark map of human brain’s gene activity holds clues to Alzheimer’s disease and more
Nature, Published online: 23 September 2026; doi:10.1038/d41586-026-02947-xThe atlas of gene expression in the prefrontal cortex was created using samples from almost 1,500 donors of all ages — from infants to centenarians.
Mapping in nearly 1.5 thousand donors reveals changes in immune and support cells affect brain health throughout life
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