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Scientists Discover Bone 'Exercise Switch': GPR133 May Restore Skeletal Density and Fight Osteoporosis

Medical conventions have long treated osteoporosis as a condition of inevitable decline, focusing treatment almost exclusively on slowing the loss of what remains. Bones slowly weaken in silence until a sudden fracture reveals the damage. However, a breakthrough from Leipzig University is challenging this defensive approach. Researchers have identified a specific receptor, GPR133 (ADGRD1), that functions as a biological “exercise signal” within …
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Intelligent Living broke the news in on Sunday, December 14, 2025.
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