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Eagles Running Back Saquon Barkley Leaves Game Against Rams with Apparent Hamstring Injury

Saquon Barkley was replaced by Tank Bigsby after a lengthy evaluation, and the Eagles called him questionable to return.

  • On Sunday, Philadelphia Eagles running back Saquon Barkley left the game against the Los Angeles Rams in the first quarter with an apparent hamstring injury and was officially designated questionable to return.
  • The Eagles entered the matchup already dealing with significant personnel losses, including All-Pro offensive tackle Lane Johnson ruled out for personal reasons and wide receiver DeVonta Smith sidelined with a hamstring injury.
  • Barkley sustained the injury during a 6-yard run in the first quarter, visibly struggling as he hobbled toward the sideline. He walked to the locker room after evaluation in the medical tent.
  • Backup running back Tank Bigsby immediately stepped in to replace Barkley, while running back Will Shipley remains available for third-down situations. Philadelphia relies heavily on the running game, making depth at the position critical.
  • Though the Eagles hope to return Barkley quickly, his status remains uncertain due to hamstring injury recovery timelines. Barkley has not had recorded hamstring strains since 2018, but his availability remains pivotal for the 2026 season.
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Ottumwa CourierOttumwa Courier
+8 Reposted by 8 other sources
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Eagles running back Saquon Barkley leaves game against Rams with hamstring injury

Philadelphia Eagles running back Saquon Barkley was ruled out for the rest of Sunday’s game against the Los Angeles Rams after he left in the first quarter with a hamstring injury. Barkley was hurt on a 6-yard run in the…

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Owensboro Messenger-Inquirer broke the news on Sunday, October 4, 2026.
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