US EditionOHSU Researchers Create Human Eggs From Skin Cells, Pointing to New Frontier in Fertility Treatment
OHSU researchers created fertilizable human eggs from skin cells despite chromosome abnormalities; about 9% reached early embryo stage, with clinical use predicted in 10 to 15 years.
- On Tuesday, researchers at Oregon Health & Science University transformed human skin cells into eggs that can be fertilized, publishing their study in Nature Communications.
- Using a nucleus-swap technique, the team removed the donor egg nucleus, replaced it with a human skin cell nucleus, then induced cells to discard extra chromosomes and injected donated sperm.
- In total, the team produced 82 eggs, but most embryos stopped developing after a few divisions; about 9% reached the blastocyst stage in lab dishes, though all were genetically abnormal.
- Experts predict clinical readiness in 10 to 15 years as scientists call the work an early proof-of-concept far from medical use, with Dr. Paula Amato urging testing in nonhuman primates and cautioning on pregnancy risks for older mothers.
- Funding and ethical controversies are already emerging as federal law banning federal funding for embryo-destructive research limits support, while critics warn of ethics and a "slippery slope".
19 Articles
19 Articles
Scientists Turn Skin Cells Into Human Eggs In Infertility Breakthrough
What if having children in the future didn’t depend on age, fertility, or even biology in the traditional sense? That’s the possibility raised by a groundbreaking study out of the US, where scientists have, for the first time, turned human skin cells into eggs. And even fertilised them with sperm in the lab.The process, called in-vitro gametogenesis (IVG), is still in its infancy. Researchers warn it could take at least a decade before it’s anyw…
Creating Babies Without Mothers Must Remain Frankensteinian Fiction
Scientists are calling it a pioneering DNA breakthrough – a Frankensteinian development where material from skin cells are transformed into human eggs capable of being fertilized and turned into human embryos. What this means is scientists creating a baby without the need of a mother. Sadly, it’s not merely theoretical. It’s already taken place at a laboratory inside the Oregon Health and Science University. “It is very preliminary work at this …
Same-sex couples could soon share DNA with their baby in scientific breakthrough
OHSU researchers fertilise eggs made from human skin DNA, meaning same-sex couples could be genetically linked to their child in the future The post Same-sex couples could soon share DNA with their baby in scientific breakthrough appeared first on Attitude.
From AI roasts to build-a-baby to orbital FedEx: the future is officially weird
From skin to egg: scientists pull off a sci-fi style fertility hack Source: Reuters Move over, sci-fi movies — real scientists just turned human skin cells into eggs. Yep, ordinary skin cells. Researchers at Oregon Health & Science University pulled off the feat by sliding the DNA from a skin cell into a donor egg and giving it a little cellular “reboot.” The result? Lab-made eggs that could actually be fertilized. A few of these experimental eg…
The ethical implications of creating eggs and sperm from skin cells are complex and delicate
The production of eggs in the laboratory could help infertile women to have their own children.
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