US Edition‘Poop pills’ developed in London show promise for cancer patients in early trial
Early trials show fecal microbiota transplant capsules improve immunotherapy response rates to 75-80% and reduce toxic side effects in kidney cancer patients, researchers say.
- New studies published in Nature Medicine show LND101 capsules from Lawson Research Institute reduce immunotherapy toxicity and improve responses in kidney, lung, and melanoma cancers, tested at LHSCRI and CRCHUM.
- Processed stool capsules reshape patients' gut microbiome by using FMT capsules from healthy stool donors to restore patient gut microbiome and eliminate harmful bacteria.
- Trial data show substantially improved response in lung and melanoma patients, with 80 per cent of patients with non-small-cell lung cancer and 75 per cent of melanoma patients responding after FMT capsules .
- In the kidney cancer trial, researchers found only one participant had serious side effects and reported a 50 to 60 per cent reduction in symptoms, improving treatment tolerance for advanced kidney cancer patients.
- As a next step, researchers at Lawson Research Institute and CRCHUM are scaling LND101 production and expanding FMT testing in the pan-Canadian Canbiome2 randomized controlled trial.
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16 Articles
The results published by Nature Medicine show how this non-traditional approach can make a qualitative shift in the treatment of several types of malignant neoplasms, by enhancing the patient's immune system's response and reducing the toxic burden of current treatment. Researchers have tested the safety and effectiveness of integrating FMT capsules with standard immune treatment, as they have found that these ad hoc capsules have significantly …
NewScientist
Anti-Aging, Acupuncture and Health NewsFaecal transplants could boost the effectiveness of cancer treatments
Adults with kidney cancer who received faecal microbiota transplants on top of their existing drugs did better than those who had placebo transplants as their add-on intervention
Fecal transplant capsules show promising results in clinical trials for multiple types of cancer
Fecal microbiota transplants (FMT) can dramatically improve cancer treatment, suggest two groundbreaking studies published in the Nature Medicine journal. The first study shows that the toxic side effects of drugs to treat kidney cancer could be eliminated with FMT. The second study suggests FMT is effective in improving the response to immunotherapy in patients with lung cancer and melanoma.
‘Poop pills’ developed in London show promise for cancer patients in early trial
New research shows that healthy poop is again improving the lives of cancer patients. Poop pills developed at Lawson Research Institute have shown promise in the treatment of pancreatic, skin, and breast cancer.
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