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Pinetree Therapeutics Announces Exercise of Option to License EGFR Degrader Program by AstraZeneca

  • AstraZeneca has exercised its option to obtain an exclusive global license for PTX-299, a bispecific antibody degrader targeting EGFR, from Pinetree Therapeutics.
  • This option exercise follows encouraging preclinical progress and marks a key milestone in collaboration between Pinetree Therapeutics and AstraZeneca.
  • AstraZeneca will take responsibility for global development and commercialization of PTX-299 under the agreement.
  • Pinetree Therapeutics will receive a $25 million payment due to AstraZeneca's option exercise, with the total potential value of the agreement exceeding $500 million.
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Pinetree Therapeutics Announces Exercise of Option to License EGFR Degrader Program by AstraZeneca

CAMBRIDGE, Mass., April 29, 2026

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PR Newswire broke the news in United States on Wednesday, April 29, 2026.
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