One Antidepressant Deprescribing Strategy Topped Others in Preventing Relapse

Experts reveal most effective way of coming off antidepressants

This approach, known as tapering, has been found to significantly lower the risk of depression relapse

Slow tapering plus therapy most effective strategy for stopping antidepressants, research finds

For adults who have recovered from depression with the help of antidepressants, gradually reducing medication together with psychological support appears to be as effective as remaining on antidepressants for preventing relapse, according to a systematic review and network meta-analysis of 76 randomized controlled trials, published in The Lancet Psychiatry.

One Antidepressant Deprescribing Strategy Topped Others in Preventing Relapse

(MedPage Today) -- Slow tapering of antidepressants with psychological support was as effective as antidepressant continuation in preventing relapse among patients with remitted depression, a systematic review and network meta-analysis of randomized...

What is the best way to come off antidepressants? A systematic review and network meta-analysis

Antidepressants are an effective treatment for moderate to severe depression and anxiety. Once patients are better, they may choose to stop taking their antidepressant and it’s important this is done safely and in a way to best reduce the risk of relapse. In the most comprehensive network meta-analysis to date, researchers from Italy have carried out a review of trials comparing different antidepressant discontinuation strategies and how effecti…