Oldest Human Brain Cells Grown in Lab 'Recorded Passage of Time'
- On Wednesday, Harvard University researchers reported growing human brain organoids for a record seven years, with peppercorn-sized clumps maturing similarly to those inside human heads.
- Normally, lab-grown organoids survive only a few months, limiting research to early developmental stages; this study overcomes those constraints by extending observation beyond initial growth phases.
- Published in the journal Nature, the study found organoids 'recorded the passage of time and retain a memory of the developmental steps already performed,' showing aging signs like myelination.
- Researchers created a 'chimera' by mixing cells from older organoids with young ones; older cells produced mature neurons, showing cells use their history to determine future behavior.
- Neuroscientist Maria Di Biase called the long-term growth 'an incredible feat,' and scientists hope these mature models will help test new medications and reveal how autism and schizophrenia progress.
22 Articles
22 Articles
ussanews.com
conservativeamericatoday.comScientists Grow Time-Tracking Brains
Scientists kept living human brain organoids alive up to seven years and found they track time as they mature, marking a new milestone for biology. Story Snapshot Researchers cultured human brain organoids for five years, with some reaching seven years, the oldest yet. The organoids showed molecular changes that matched how a child’s brain develops...
Peppercorn-sized pieces of human brains grown in a lab for a record seven years have aged in a similar way to the ones inside our heads, suggesting they have “recorded the passage of time”, scientists claimed today. These tiny chunks, called organoids, are being grown from stem cells by scientists around the world in...
TVA Nouvelles
Le Journal de QuebecCreated in laboratories, tiny blocks of brain have been studied for years
Unprecedented: Scientists Have Built Miniature Brains That Experience The Passage Of Time
Our brains comprise 86 billion neurons and the trillions of connections between them, whipping up an orchestrated storm of electricity and chemicals that pulse within a 3-pound lump of jellified fat, protein, and water.
The researchers found that brain organoids continued to change and mature over the years, even though they did not develop in an embryo or human body.
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