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Week 5 NFL Odds, Lines, Predictions: Picks for Every Game This Week

Microsoft Copilot AI achieved a 9-6-1 record in Week 5, improving its 2025 NFL season prediction to 39-24-1 with detailed player injury and performance analysis.

Summary by CBS Sports
SportsLine's advanced model has locked in its Week 5 NFL betting picks from 10,000 simulations

2 Articles

CBS SportsCBS Sports
Center

Week 5 NFL odds, lines, predictions: Picks for every game this week

SportsLine's advanced model has locked in its Week 5 NFL betting picks from 10,000 simulations

·United States
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USA TodayUSA Today
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NFL Week 5 predictions by Microsoft Copilot AI for every game

Microsoft Copilot AI posted a winning record with its picks for a third consecutive week. How will it fare with bye weeks kicking up in Week 5?

·United States
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USA Today broke the news in United States on Thursday, October 2, 2025.
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