Scientists Just Reprogrammed Brain Immune Cells to Fight Alzheimer's Plaques and the Memory Results Are Striking
3 Articles
3 Articles
Scientists Just Reprogrammed Brain Immune Cells to Fight Alzheimer's Plaques and the Memory Results Are Striking
A June 19, 2026 study in Cell Death & Disease found molecule OLE reprograms microglia to contain amyloid plaques, reducing toxicity and improving memory in Alzheimer's models.
Molecule “reprograms” the brain’s defenses against Alzheimer’s disease
A team led by researcher José Vicente Sánchez Mut at the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University of Elche (UMH), together with researcher Johannes Gräff at the École Polytechnique Fédérale de Lausanne (EPFL), has identified an experimental molecule capable of “reprogramming” the brain’s immune cells to restore part of their protective function against Al…
The study, led by José Vicente Sánchez Mut, researcher at the Institute of Neurosciences, a mixed center of the Miguel Hernández de Elche University and the CSIC, together with the researcher at the École Polytechnique Fédérale of Lausanne Johannes Gräf, shows that the compound OLE helps the microglye to surround and contain the beta-amyloid plates, reducing their size and toxicity.A molecule that returns to the microglye its protective function…
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