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AI Detects Pancreatic Cancer up to 3 Years Earlier, Mayo Study Shows
The model reviewed nearly 2,000 scans and found 73% of cancers before diagnosis, nearly doubling specialist detection without AI assistance.
Mayo Clinic researchers developed an AI model called REDMOD that detects pancreatic cancer up to three years before clinical diagnosis by identifying subtle changes in routine CT scans.
Pancreatic cancer is often deadly because it rarely causes symptoms in early stages; more than 85% of patients receive a diagnosis after the disease has spread, with five-year survival rates below 15%, according to the National Cancer Institute.
Published in Gut, the study validated REDMOD using nearly 2,000 CT scans, identifying 73% of prediagnostic cancers at a median of about 16 months before diagnosis—nearly double the detection rate of specialists without AI assistance.
Researchers are advancing this work into the AI-PACED study, which evaluates how clinicians can integrate AI-guided detection into care for patients at elevated risk, such as those with new-onset diabetes.
The research, supported by the National Institutes of Health, is part of the Precure initiative, which "aims to predict and prevent disease by identifying the earliest biological changes in the body before symptoms start.