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Pitt Blows 17-Point Lead, Gets Shut Out in 2nd Half in Loss to Louisville

Miller Moss threw three touchdowns to lead Louisville’s comeback from a 17-point deficit, securing their first ACC road win at Pitt since 2012 and improving to 4-0.

  • The Louisville Cardinals defeated the Pittsburgh Panthers 34-27 in their ACC opener on Saturday at Acrisure Stadium in Pittsburgh.
  • Louisville overcame early struggles, including a 17-0 deficit caused by a pick-six and poor starts on both offense and defense.
  • Key plays included a 25-yard touchdown pass from Miller Moss to Chris Bell, a one-yard rushing touchdown by Moss, and crucial defensive turnovers.
  • Miller Moss completed 33 of 51 passes for 339 yards, three touchdowns, and led the final six-play, 30-yard drive to take a 34-27 lead.
  • The win improved Louisville to 4-0 overall and 1-0 in the ACC, highlighting their resilience while exposing concerns about penalties despite strong defense and special teams.
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The Hamilton Spectator broke the news in Hamilton, Canada on Saturday, September 27, 2025.
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