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Light-Controlled Gene Expression Platform Reportedly Doubles Standard Fed-Batch Manufacturing Performance

Prolific Machines, an Emeryville, CA-based biotech company focusing on light-controllable biomanufacturing powered by optogenetics, reported a productivity milestone of 21 g/L in a 15-day intensified fed-batch CHO run for a monoclonal antibody (mAb). This is more than double the industry standard of below 10 g/L, and the company is on track to reach its goal of 25 g/L in fed-batch by the end of 2026, according to company officials. Prolific’s li…

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GEN - Genetic Engineering and Biotechnology News… broke the news on Wednesday, May 6, 2026.
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