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Life uses 4 DNA letters. Scientists just made 8 work

Summary by Science Daily
Researchers at UC San Diego have demonstrated that a key cellular enzyme can accurately read an eight-letter genetic alphabet, doubling the four letters used by all known life on Earth. Detailed imaging revealed that RNA polymerase handles synthetic DNA letters in surprisingly similar ways to natural ones. The finding brings scientists closer to building expanded genetic systems that could perform entirely new biological functions.

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The source code of life changes forever: the cellular enzyme learns to read an 8-letter DNA, opening the way to smart drugs and a new biotechnology market.The article Life doubles the alphabet: 8-letter DNA breaks down the monopoly of nature and opens a new industrial era comes from Economic Scenarios.

A cellular enzyme has successfully read DNA with four natural and four synthetic bases, opening new possibilities in biology.

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ecotopical.com broke the news on Saturday, September 5, 2026.
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