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LDB1 Regulates Gene Expression and Chromatin Structure in Pluripotency and Lineage Differentiation

Researchers generated LIM domain-binding 1 (Ldb1)(-/-) ESCs using CRISPR/Cas9 editing and observed a reduction in key stem cell factors SOX2 and KLF4 upon LDB1 loss. [Nucleic Acids Research] Full ArticleGraphical Abstract
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Stemwell Science News broke the news in on Wednesday, January 28, 2026.
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