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Daraxonrasib Demonstrates Initial Antitumor Activity in RAS-Mutant Lung Cancer

More than 30% of patients with RAS-mutated non-small-cell lung cancer saw tumors shrink in a small trial, researchers said.

Summary by Medical Xpress
Daraxonrasib, an oral RAS inhibitor therapy, achieved durable responses in pretreated patients with RAS-mutant non-small cell lung cancer (NSCLC) in a phase 1/2 trial led by The University of Texas MD Anderson Cancer Center.

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The drug Rasonque (daraxonrasib), which received historic FDA approval by doubling the survival time in pancreatic cancer, has also been shown to be effective against lung cancer, the deadliest type of cancer.

·Istanbul, Türkiye
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Mariasanchezmonge Oncology Study in 'NEJM' Daraxonrasib, the drug that has initiated a revolution in the treatment of pancreatic cancer, also shows promising results in lung cancer. As pointed out by the authors of the study published in The New England Journal of Medicine, there are well-founded reasons to rely on its efficacy in other types of tumors. In this case, it is known that RAS mutations, which constitute the target of this inhibitor, …

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Nature broke the news in London, United Kingdom on Wednesday, September 2, 2026.
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