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Eggs fertilized with material from human skin cells for first time

OHSU researchers created 82 fertilizable eggs from skin cells, with 9% reaching early embryo stage, marking a key step toward infertility treatments for women and same-sex couples.

  • Researchers at Oregon Health and Science University developed a technique that turns DNA from skin cells into human eggs capable of producing embryos.
  • The experimental technique involves chromosomal abnormalities in the embryos and may require 10 to 15 years for clinical use.
  • Paulo Amato noted that the work is preliminary and highlighted health risks for older pregnant women.
  • This method could allow older women and same-sex couples to possibly have genetically related children.
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American scientists have created early human embryos for the first time by manipulating DNA taken from human skin cells and then fertilizing them with sperm. The technique could overcome infertility due to age or disease. The method could theoretically allow same-sex couples to have genetically related children. But researchers still have many years of work ahead of them.

Lean Left

Researchers have changed human skin cells in such a way that they could be fertilized with sperm. Older women or same-sex couples could open up completely new possibilities.

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The method can help with infertility and allow same-sex couples to have a child genetically related to them, but it still takes time for it to work well.

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ohsu.edu broke the news in on Tuesday, September 30, 2025.
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