Integrating Anatomy and Biology for a Better Pancreatic Cancer Prognosis

Integrating anatomy and biology for a better pancreatic cancer prognosis

Pancreatic ductal adenocarcinoma (PDAC) is notoriously difficult to treat due to its aggressive nature and limited prognostic tools. While the traditional staging systems, such as the TNM classification, focus on anatomical factors, they fall short in providing a comprehensive prognosis. The Tianjin Grading System addresses this gap by integrating anatomical, biological, and patient condition factors.

Integrating Anatomy and Biology for a Better Pancreatic Cancer Prognosis

Recent advancements in pancreatic cancer prognosis have led to the development of the Tianjin Grading System, a tool integrating both anatomical resectability and tumor biological parameters. This system uses key clinical indicators, such as resectability status, lymph node metastasis, serum CA19-9 levels, and the Prognostic Nutritional Score (PNS) to stratify patients into four distinct risk categories. By offering a more comprehensive assessmen