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Introducing the 'Human Repairome,' a Catalog of DNA 'Scars' that May Help Define Personalized Cancer Treatments

Summary by Medical Xpress
You can always be judged by your scars. This is the idea that sums up one of the new advances in basic and biomedical research published in the journal Science by the Spanish National Cancer Research Center (CNIO). It is the "human REPAIRome"—a name that refers to the repair of breaks in the DNA molecule.

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The fight against cancer, in its multiforms and often fundamental variations, has brought another point in favor of the understanding of cancers and therefore the possibilities of treatment or even cure. A unique archive, which collects the scars left by the repairs of the human DNA, promises to change the future of doctors and patients. It is called human Riparioma and is the first world catalog of mutations generated by the cellular mechanisms…

·Rome, Italy
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A CNIO team details the 'human reparoma', a resource that will be available open to the scientific community and aims to help combat different biomedical problems Read

·Madrid, Spain
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A CNIO group has identified the 20,000 types of scars left in human DNA repaired after a break. It has then organized them on a web site, the portal of human repairoma, which is available to the world scientific community. Thus, human repairoma becomes the catalogue of scar patterns in repaired human DNA. It is very valuable information as basic knowledge, but also from the medical point of view. For example, being able to interpret the scar pat…

We are our genes but, above all, we are the result of the process by which each cell suffers and repairs damages constantly. It is an invisible dynamic and that in most cases passes totally unnoticed but that, as soon as it stops, it leads to a disease. According to the magazine 'Science', a team of Spanish scientists has created for the first time a map with information about more than 20,000 molecular scars that a body suffers and data on how …

Tell me what your scars look like, and I'll tell you who you are. It's the idea that sums up one of the new breakthroughs in basic and biomedical research published today by Science magazine, and that it's an achievement of the National Center for Oncological Research (CNIO). It's the 'human reparoma' – in English REPAIRome – that refurbishes the repair of breaks in the DNA molecule. A CNIO group has identified the 20,000 types of scars left in …

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www.diariolibre.com broke the news in on Thursday, October 2, 2025.
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