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HIV Tat Undermines Cellular Defenses, Enabling TB Infection
Tuberculosis (TB) remains the leading cause of death among people living with HIV. Although HIV-1 and Mycobacterium tuberculosis (Mtb) coinfection remains a major public health concern, this problem is not well characterized. Even patients on effective antiretroviral therapy (ART) face a four- to seven-fold higher risk of TB than those without HIV. A new study now reveals why: HIV deploys one of its own proteins to sabotage the immune system’s c…
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1 Articles
HIV Tat Undermines Cellular Defenses, Enabling TB Infection
Tuberculosis (TB) remains the leading cause of death among people living with HIV. Although HIV-1 and Mycobacterium tuberculosis (Mtb) coinfection remains a major public health concern, this problem is not well characterized. Even patients on effective antiretroviral therapy (ART) face a four- to seven-fold higher risk of TB than those without HIV. A new study now reveals why: HIV deploys one of its own proteins to sabotage the immune system’s c…
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